This volume includes several invited lectures given at the International Workshop "Analysis, Partial Differential Equations and Applications", held at the Mathematical Department of Sapienza University of Rome, on the occasion of the 70th birthday of Vladimir G. Maz'ya, a renowned mathematician and one of the main experts in the field of pure and applied analysis. The book aims at spreading the seminal ideas of Maz'ya to a larger audience in faculties of sciences and engineering. In fact, all articles were inspired by previous works of Maz'ya in several frameworks, including classical and contemporary problems connected with boundary and initial value problems for elliptic, hyperbolic and parabolic operators, Schrödinger-type equations, mathematical theory of elasticity, potential theory, capacity, singular integral operators, p-Laplacians, functional analysis, and approximation theory. Maz'ya is author of more than 450 papers and 20 books. In his long career he obtained many astonishing and frequently cited results in the theory of harmonic potentials on non-smooth domains, potential and capacity theories, spaces of functions with bounded variation, maximum principle for higher-order elliptic equations, Sobolev multipliers, approximate approximations, etc. The topics included in this volume will be particularly useful to all researchers who are interested in achieving a deeper understanding of the large expertise of Vladimir Maz'ya.