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Indigo Chromatin: Structure, Function, and Human Disease | Erin Mills Town Centre
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Chromatin: Structure, Function, and Human Disease offers readers a comprehensive and up-to-date overview of the remarkable advances in chromatin research over the past 50+ years. The book covers both the historical context and recent discoveries in chromatin structure, remodeling, histone modification, phase transitions, and nuclear compartmentalization. It further explores chromatin-regulated processes, including transcriptional activation and repression, DNA replication, replication origins, DNA repair, and epigenetic inheritance, with a focus on replication-coupled nucleosome assembly.The text also discusses chromatin modulation and signaling during DNA damage and repair, as well as the components and functions of chromatin in human disease and therapeutic innovations. With the rapid emergence of new methods for structural and genomic sequence analysis and engineering, research on chromatin structure, epigenetic signaling, and chromatin dynamics has become a powerful and rapidly growing interdisciplinary field. This book integrates fundamental models of chromatin structure with the most advanced studies of genome function and their applications in modern medicine.
Chromatin: Structure, Function, and Human Disease offers readers a comprehensive and up-to-date overview of the remarkable advances in chromatin research over the past 50+ years. The book covers both the historical context and recent discoveries in chromatin structure, remodeling, histone modification, phase transitions, and nuclear compartmentalization. It further explores chromatin-regulated processes, including transcriptional activation and repression, DNA replication, replication origins, DNA repair, and epigenetic inheritance, with a focus on replication-coupled nucleosome assembly.The text also discusses chromatin modulation and signaling during DNA damage and repair, as well as the components and functions of chromatin in human disease and therapeutic innovations. With the rapid emergence of new methods for structural and genomic sequence analysis and engineering, research on chromatin structure, epigenetic signaling, and chromatin dynamics has become a powerful and rapidly growing interdisciplinary field. This book integrates fundamental models of chromatin structure with the most advanced studies of genome function and their applications in modern medicine.
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