Crop model intercomparison and improvement are required to advance understanding of the impact of future climate change on crop growth and yield. The initial efforts undertaken in the Agriculture Model Intercomparison and Improvement Project (AgMIP) led to several observations where crop models were not adequately simulating growth and development. These studies revealed where enhanced efforts should be undertaken in experimental data to quantify the carbon dioxide × temperature × water interactions in plant growth and yield. International leaders in this area held a symposium at the 2013 ASA, CSSA, and SSSA Annual Meeting to discuss this topic. This volume in the Advances in Agricultural Systems Modeling series presents experimental observations across crops and simulation modeling outcomes and addresses future challenges in improving crop simulation models. IN PRESS! This book is being published according to the “Just Published” model, with more chapters to be published online as they are completed.