This conference LNAI  14502 volume constitutes the workshop proceedings of 22nd Mexican International Conference on Artificial Intelligence, held in November 2023 in Mérida, Yucatán, México. The total of 34 papers presented in this volume was carefully reviewed and selected from 54 submissions.The proceedings of MICAI 2023 workshops are structured into three sections:- WILE 2023: 16th Workshop on Intelligent Learning Environments- HIS 2023: 16th Workshop of Hybrid Intelligent Systems- CIAPP 2023: 5th Workshop on New Trends in Computational Intelligence and Applications