This book is devoted to the critical and evolving field of periprosthetic joint infection (PJI), offering a comprehensive review of the latest advances in its prevention, diagnosis, and treatment. With contributions from leading experts, this volume provides invaluable insights into managing PJI across various joints, including the shoulder, elbow, hip, knee, and ankle. The chapters cover essential topics such as general concepts of PJI, diagnostic techniques, antibiotic prophylaxis, and specific challenges associated with different types of joint arthroplasty. Readers will explore risk factors, debridement strategies, revision surgeries, and innovative treatments like knee arthrodesis. This book is a must-read for anyone seeking to stay abreast of cutting-edge research and clinical practices in the field of PJI. Researchers in orthopedics, infectious disease specialists, surgeons, and healthcare professionals involved in joint arthroplasty will find this book particularly beneficial. This book serves as an essential resource for understanding the complexities of PJI and offers practical solutions to improve patient outcomes. It equips both seasoned practitioners and residents entering the field with essential knowledge and tools to tackle one of the most challenging complications in joint replacement surgery.