This book is first part of the 3 volume set focusing on basic and advanced methods for using microbiology as an entrepreneurial venture. This volume explains the entrepreneurship skills for production, cost-benefit analysis and marketing of bio-fertilizers, bio-pesticides, bio-insecticides, seaweed liquid biofertilizer, and phosphate solubilizers. Chapters cover the applications of microorganisms in small and large scale production to achieve a sustainable output. The book provides essential knowledge and working business protocols from all related disciplines in agribusiness, organic farming, and economic integration. This book is useful to graduate students, research scholars and postdoctoral fellows, and teachers who belong to different disciplines via Botany, Agriculture, Environmental Microbiology and Biotechnology, Plant Pathology, and Horticulture. Next two volumes are focused on food and industrial microbiology.