This book is a frontier reference offering combinatorial technology by integrating two mainstream tools of artificial intelligence and nanotechnology in agricultural applications, towards smart, precision, and sustainable farming. These smart tools, so-called "AI-enabled nanotechnology", cover intelligent nanoparticles, working as nano-sensors, nano-fertilizers, nano-pesticides, and nano-carriers for targeted delivering biostimulants such as plant growth-promoting rhizobacteria, and additionally, nucleic acids in advancing genetic engineering via CRIPSR/Cas technology and epigenetic modulations via RNA technology. This book proposes promising crop-improving strategies constructed by AI-enabled nanotechnology with systems biological and omics tools, to obtain future crops with climate-ready capacities against temperature, water, and various potential environmental factors under a globally changing climate. The readers include students, teachers, professors, researchers, and experts, in a wide range of agricultural sectors, in particular those who are interested or learning materials science, nano-science, nanotechnology, agricultural biotechnology, bioinformatics involving AI technology, data science, plant physiology, and crop breeding.