The book is a collection of research papers presented at the First International Conference on International Conference on Ambient Intelligence in Health Care (ICAIHC 2021) organized by Institute of Technical Education and Research, Siksha 'O- Anusandhan (Deemed to be University) University, Bhubaneswar, India, during April 15-16, 2022. It includes papers in the research area of e-health care, telemedicine, other medical technologies, life support systems, fast detection and diagnoses, developed technologies and innovative solutions, bioinformatics, and solutions for monitoring smart intelligent systems in health care.