This book constitutes the thoroughly refereed conference proceedings of the First International Workshop on Design and Architecture for Signal and Image Processing, DASIP 2022, held in Budaypest, Hungary in June 2022. The 13 full included in the volume were carefully reviewed and selected from 32 submissions. They are organized in the following topical sections: leading signal, image and video processing and machine learning in custom embedded, edge and cloud computing architectures and systems.