"Lock your doors, cover your windows, and avoid making noise. Do not, for any reason, go outside." When James witnesses a brutal killing outside his home, he must choose between seeking help or waiting for rescue in a city overrun by the infected. Trapped in his lab as the city descends into chaos, scientist Daniel waits for the infected surrounding the building to disperse. When they refuse to budge even days later, he realizes he's going to be stuck there for a long time. The already frayed relationship between Heather and her sister with autism will be put to the test as they brave the streets overrun by the infected. Pierce is a soldier sent on a secret mission inside the quarantine zone. What he discovers inside the dead city will have him question the orders he's been given. Krista's son shows signs of infection, but she's going to do everything in her power to protect him. Caught in the middle of chaos, Ben must make a choice between risking his safety to find his wife or focusing on his own survival. Who will make it out alive in a city where the infected roam free?