This book constitutes the refereed proceedings of the 5th EAI International Conference on Industrial Networks and Intelligent Systems, INISCOM 2019, held in Ho Chi Minh City, Vietnam, in August 2019. The 25 full papers were selected from 39 submissions and are organized thematically in tracks on telecommunications systems and networks; industrial networks and applications; hardware and software design and development; information processing and data analysis; signal processing; security and privacy.