This book explores how Jenny Sabin Studio and the Sabin Lab at Cornell University pioneer biosynthetic architecture through rigorous transdisciplinary collaboration across design, science, and technology. At the intersection of biology,  computation, and material innovation, their work demonstrates how adaptive, resilient structures can respond to urgent ecological and social imperatives. Featuring built projects, experimental research, and essays by leading voices in architecture and design, the book demonstrates how radical new models of practice linking lab and studio-are transforming pedagogy, design research, and how we imagine architecture today.