This book discusses the diversity of marine actinobacteria with a special focus on the indigenous species. It covers all derivatives from the marine actinobacteria including enzyme, enzyme inhibitors and antibiotics. It then further delves into the isolation methods, screening methods and modern techniques that cis employed to reveal its potentials. The industrially important bioactive producing genera covered in the book are Actinomadura, Actinoplanes, Amycolatopsis, Marinispora, Micromonospora, Nocardiopsis, Saccharopolyspora, Salinispora, Streptomyces and Verrucosispora. The book also discusses the impact of advancements in whole genome sequencing and synthetic biology on the discovery of new bioactive compounds from marine actinomycetes. It then further explains the applications of this species in extraction of biofuels and for sustainable agriculture. This book is a valuable resource for researchers, industrialists and students pursuing marine actinobacteria or marine bioprospecting.