In this issue of Emergency Medicine Clinics , guest editors Drs. Semhar Z. Tewelde and Whitney Johnson bring their considerable expertise to the topic of Misses that Matter: The Art of Emergency Medicine . The concept of "misses that matter" emphasizes the significance of paying attention to, recognizing, and addressing small details to ensure comprehensive and effective patient care during emergencies. In this issue, top experts highlight the artistry and nuance involved in managing medical crises, demonstrating the importance of thoroughness and attention to detail in the practice of emergency medicine.