This book constitutes the proceedings of the 10th European Conference on Modelling Foundations and Applications, ECMFA 2014, held as part of STAF 2014, in York, UK, in July 2014. The 14 foundation track papers and the 3 applications track papers presented in this volume were carefully reviewed and selected from 58 submissions. They are on all aspects of MDE, including topics such as model provenance; model transformations and code generation; model synthesis; model-driven testing; formal modeling approaches; business modeling; and usability of models.