Experimental syntax is an area that is rapidly growing as linguistic research becomes increasingly focused on replicable language data, in both fieldwork and laboratory environments. The first of its kind, this handbook provides an in-depth overview of current issues and trends in this field, with contributions from leading international scholars. It pays special attention to sentence acceptability experiments, outlining current best practices in conducting tests, and pointing out promising new avenues for future research. Separate sections review research results from the past 20 years, covering specific syntactic phenomena and language types. The handbook also outlines other common psycholinguistic and neurolinguistic methods for studying syntax, comparing and contrasting them with acceptability experiments, and giving useful perspectives on the interplay between theoretical and experimental linguistics. Providing an up-to-date reference on this exciting field, it is essential reading for students and researchers in linguistics interested in using experimental methods to conduct syntactic research.