Allen Seltzer is an introverted divorcee who is struggling with a fear of people. When cognitive psychologist, Monica Forthmore, locks him in a room as part of an experiment to study irrational fear, he finds himself in close proximity with four strangers who are struggling with fears of their own. Now, the five strangers have to find a way to survive the grueling experiment while facing some of their darkest demons. Will they learn to control their fears before their fears control them?