Salome Azul, daughter of a powerful politician, flees Buenos Aires at the height of the Argentinian civil war. In London she enlists the help of Irishman Sean Ryan to open The Nightingale, a high-class brothel and opium den that will be used to entrap and blackmail London's political elite. In doing so she will make enemies, but it is the demons Salome has carried with her from Argentina that will prove her most relentless foe. In order to survive, she must eliminate all weakness from her character. Doing so will mean cutting away all she cherishes most. In the pursuit of power, unrelenting sacrifice is what decides who lives and dies.