Love. Desire. Vengeance. A deadly alchemy. When Rebecca Palmer's new husband opens a pharmacy in Victorian Edinburgh, she expects to live the life of a well-heeled gentlewoman. But her ideal turns to ashes when she discovers her husband is not what he seems. As Rebecca struggles to maintain her dignity in the face of his infidelity and strange sexual desires, Alexander tries to pacify her so-called hysteria with a magical new chemical creation: a wonder-drug he calls heroin. Rebecca's journey into addiction takes her further into her past, and her first, lost love, while Alexander looks on, curiously observing his wife's descent. Meanwhile, Alexander's desire to profit from his invention leads him down a dangerous path that blurs science, passion, and death. He soon discovers that even the most promising experiments can have unforeseen and deadly consequences.