This novel is a thrilling tale involving a train journey from Paris to Rome, where the plot likely unfolds during the train ride or around the events associated with it. It could be a mystery or an adventure story set against the backdrop of the train travel, featuring suspenseful events, intrigues, and possibly criminal elements.Griffiths was known for his engaging storytelling and mysteries, and "The Rome Express" might contain elements of suspense, unexpected twists, and a vivid portrayal of the train journey as a central element of the plot. This work is considered one of Griffiths' notable contributions to the mystery and adventure genre.