Over lunch, Dr Jack Broccoli learns from Dr Larry Faber, a friend from medical school, about an amazing drug he has developed called Ambrotine. It seems that it reverses aging and cures almost any disease. Larry needs experimental subjects, so Jack volunteers some of his own nursing home patients and the results are positive beyond all expectations. There are however, a few unexpected side effects. Jack finds himself in trouble with his licensing authority and on the run from Pharmex, a ruthless drug company interested in the enormous financial promise of the drug. He also has problems caused by his generous desire to be of service to womankind. He falls in love with Karen but has to flee with her to an undisclosed location as a craze for Ambrotine sweeps the world...