O’Keeffe’s® Working Hands® Hand Cream is a concentrated hand cream that heals, relieves and repairs extremely dry, cracked hands. When used daily, O’Keeffe’s® Working Hands® is clinically proven to: *Instantly boost moisture levels *Creates a barrier on the skin’s surface *Help prevent further moisture loss It is safe and effective for people with diabetes. Representative Photos: Before and After Hand Images. One week usage period. Cream was applied before bed and three times day.